Asymmetric Hydrogenation of B-pin Containing
Ketones and Derivatives
Title
Asymmetric Hydrogenation of B-pin Containing
Ketones and Derivatives
Ketones and Derivatives
Subject
Chemistry
Description
Molecules, just like many objects, can exist in structurally iden�cal but mirror image forms known as ‘enan�omers’ (Figure 1 – like
your hands), each of which can have a different biological effect.1 A 50-50 mixture of enan�omers is made through tradi�onal synthe�c methods of reducing ketones to enan�omeric alcohols (Scheme 1), whereas using asymmetric catalysts can predominantly
create one enan�omer,2 which is essen�al (and indeed a legal requirement) for the synthesis of many important known and novel
molecules, such as pharmaceuticals, agrochemicals and other fine chemicals.
your hands), each of which can have a different biological effect.1 A 50-50 mixture of enan�omers is made through tradi�onal synthe�c methods of reducing ketones to enan�omeric alcohols (Scheme 1), whereas using asymmetric catalysts can predominantly
create one enan�omer,2 which is essen�al (and indeed a legal requirement) for the synthesis of many important known and novel
molecules, such as pharmaceuticals, agrochemicals and other fine chemicals.
Creator
Efstratios Nikolaidis
Files
Collection
Citation
Efstratios Nikolaidis, “Asymmetric Hydrogenation of B-pin Containing
Ketones and Derivatives,” URSS SHOWCASE, accessed December 22, 2024, https://urss.warwick.ac.uk/items/show/180.
Ketones and Derivatives,” URSS SHOWCASE, accessed December 22, 2024, https://urss.warwick.ac.uk/items/show/180.