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              <text>Active-ingredient loaded structures, integrated with reversibly covalently linked peptide, were fabricated using digital light processing (DLP) type VAT photopolymerization, in the absence of water. Bisacryloyl crystamine (BAC) was incorporated into printing resin for the introduction of disulfide functionality into some crosslinks. The uptake and subsequent release of lanreotide was monitored and facilitated via a reversible thiol-disulfide exchange controlled by addition of tris(2-carboxyethyl) phosphine (TCEP). The method was successful in cost and time efficiently producing structures capable of controlled release of a therapeutic peptide.</text>
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              <text> Extreme Type Ia supernovae present challenges for our understanding of thermonuclear explosion physics. A census of Type Ia supernova theoretical models for various parameter spaces was conducted. This enabled a comparative analysis of the diversity and overlap between distinct explosion scenarios and observed data. With the assistance of my supervisor, Dr Mark Magee, I was able to conclude the physical properties driving this overlap.  </text>
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              <text>Synthetic CTs enable voxel-by-voxel mass density representation while reducing artefacts, a significant advancement for accurate dose calculations in adaptive radiotherapy. This study evaluates two synthetic algorithms—corrected CBCT (corrCBCT) and virtual CT (vCT) —against conventional CBCT with bulk density assignment. Analysing dosimetric outcomes in patients with varying anatomical changes, it was found that while the vCT offers improved mass density representation, there is no significant difference in dose distributions between the vCT and corrCBCT. The execution of hybrid registrations was critical, significantly impacting the anatomical accuracy of the vCT image. Despite differences in mass density representations between the vCT and corrCBCT, using a corrCBCT is recommended in adaptive radiotherapy to ensure current anatomical accuracy.</text>
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